Lisdexamfetamine dimesylate
Lisdexamfetamine Dimesylate, Vyvanse (lisdexamfetamine dimesylate) is a small molecule pharmaceutical. Lisdexamfetamine dimesylate was first approved as Vyvanse on 2007-02-23. It is used to treat attention deficit disorder with hyperactivity and binge drinking in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Lisdexamfetamine dimesylate, Vyvanse (discontinued: Lisdexamfetamine dimesylate)
Drug Products
FDA
EMA
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lisdexamfetamine dimesylate | ANDA | 2024-09-26 |
| vyvanse | New Drug Application | 2023-10-13 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| binge drinking | — | D063425 | — |
| attention deficit disorder with hyperactivity | EFO_0003888 | D001289 | F90 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
123 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | 4 | 9 | 13 | 28 | 13 | 65 |
| Hyperkinesis | D006948 | HP_0000752 | — | 2 | 7 | 7 | 18 | 9 | 42 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 3 | 5 | 3 | — | 11 |
| Depression | D003863 | — | F33.9 | — | 3 | 5 | 2 | — | 10 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | 3 | 3 | 1 | — | 7 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | 1 | 3 | 1 | — | 5 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | 2 | 1 | 1 | 4 |
| Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | 3 | 1 | 4 |
| Traumatic brain injuries | D000070642 | — | S06 | — | — | 1 | 1 | — | 2 |
| Brain injuries | D001930 | — | S06.9 | — | — | 1 | 1 | — | 2 |
Show 12 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bulimia | D002032 | — | F50.2 | — | 3 | 7 | — | 2 | 12 |
| Binge-eating disorder | D056912 | — | F50.2 | — | 2 | 7 | — | 2 | 11 |
| Feeding and eating disorders | D001068 | — | F50 | — | 2 | 7 | — | 1 | 10 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | 1 | 4 | — | — | 6 |
| Overweight | D050177 | — | E66.3 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Substance-related disorders | D019966 | EFO_0003890 | F13 | 1 | 3 | — | — | 1 | 4 |
| Cocaine-related disorders | D019970 | — | F14 | 2 | 2 | — | — | — | 3 |
| Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 1 | 2 | — | — | — | 2 |
| Sleep deprivation | D012892 | — | F51.12 | — | 1 | — | — | — | 1 |
| Bulimia nervosa | D052018 | EFO_0005204 | F50.2 | — | 1 | — | — | — | 1 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 1 | — | — | — | 1 |
| Sclerosis | D012598 | — | — | — | 1 | — | — | — | 1 |
| Addictive behavior | D016739 | EFO_0004347 | — | — | 1 | — | — | — | 1 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 1 | — | — | — | 1 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 7 | — | — | — | — | 7 |
| Drug misuse | D000076064 | — | — | 1 | — | — | — | — | 1 |
| Pediatric obesity | D063766 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tobacco use disorder | D014029 | — | F17 | — | — | — | — | 1 | 1 |
| Feeding behavior | D005247 | — | — | — | — | — | — | 1 | 1 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | — | 1 | 1 |
| Sleep | D012890 | GO_0030431 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Lisdexamfetamine dimesylate |
| INN | — |
| Description | Lisdexamfetamine is an amino acid amide. |
| Classification | Small molecule |
| Drug class | amfetamine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CS(=O)(=O)O.CS(=O)(=O)O.C[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN |
Identifiers
| PDB | — |
| CAS-ID | 608137-32-2 |
| RxCUI | 700810 |
| ChEMBL ID | CHEMBL1201178 |
| ChEBI ID | — |
| PubChem CID | 11597698 |
| DrugBank | DB01255 |
| UNII ID | — |
Target
No data
Variants
No data
Financial
Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,095 documents
View more details
Safety
Black-box Warning
Black-box warning for: Lisdexamfetamine dimesylate, Vyvanse
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
18,471 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use